At least 53 people were killed and over 127 others injured when a suicide bomb attack hit a mosque packed with hundreds of prayers in northwest Pakistan Friday afternoon, local Urdu TV channel Express reports.

People carry a man who was injured in a suicide bomb attack targeting Friday congregational prayers at a Mosque in the Ghandi area of Jamrud in Khyber Agency, to a local hospital in Peshawar, the capital of militancy-hit Khyber-Pakhtunkhwa province, Pakistan, 19 August 2011. [CFP]

According to the TV, the blast took place at about 02:00 p.m. local time Friday when a teenager suicide bomber aged about 16 blew himself up in a mosque at the Ghondi area of Jamrud, a district in Pakistan's northwest tribal area of Khyber Agency which borders Afghanistan.

Hundreds of people were offering Friday prayers inside the mosque when the attack took place, said local media reports.

Some reports said that over 100 people were inside the mosque hit by the blast while others put the number at 400 to 700.

Local TV footage showed that the mosque partially collapsed following the huge blast and many people were feared buried under the debris of the collapsed building.

An injured people is being sent to hospital after a suicide bomb attack hit a mosque packed with hundreds of prayers in northwest Pakistan on the afternoon of August 19, 2011.

An estimated 40 people injured in the blast were rushed to nearby hospitals while some 50 critically injured people have been shifted to the Lady Reading Hospital and other hospitals in Peshawar, a city which is about 50 kilometers away from the blast site.

As the mosque hit by the blast is located in a mountainous area and some of the injured people being shifted to Peshawar could die on the way.

Shortly after the blast was reported, both Pakistani President Asif Ali Zardari and Prime Minister Yusuf Raza Gilani issued statements strongly condemning the attack.

No group has claimed responsibility for the attack yet.

Friday's suicide blast is one of the most serious terrorist attacks in Pakistan since the killing of al-Qaida chief Osama bin Laden by the U.S. special forces in the country's northwest city of Abbottabad on May 2.