Actor Charlie Sheen was released from a New York hospital on Tuesday evening after being taken there in the early morning hours when he was found highly intoxicated in Manhattan's Plaza Hotel.

Police found the troubled star of the hit TV show "Two and a Half Men" acting drunk and incoherent in his room. The actor voluntarily agreed to go to the hospital, according to police.

Sheen's publicist Stan Rosenfield said in a statement early on Tuesday that the 45-year-old actor had reacted badly to an unspecified medication.

"What we are able to determine is that Charlie had an adverse allergic reaction to some medication and was taken to the hospital," he said.

By late Tuesday, Rosenfield said Sheen was on his way home to Los Angeles after being discharged.

Local media reported Sheen was with an unidentified woman and found drunk and naked in a trashed hotel room after a night of partying and that he had become enraged after discovering his wallet was missing. The actor had been in New York visiting his ex-wife, Denise Richards, and their two daughters.

Rosenfield seemed to knock down those reports in his statement, saying that beyond Sheen's hospitalization, "everything else is speculation."

Police said no complaints were made and there was no arrest. No criminal charges are expected.

The incident is the latest in a long line of troubles for Sheen -- the son of actor Martin Sheen -- who started performing at the age of nine.

In August, Sheen pleaded guilty to assaulting his third wife Brooke Mueller and was sentenced to 30 days in drug and alcohol rehab and placed on probation for three months. It was not immediately clear how the New York incident would impact his sentence, which was handed out in Aspen, Colorado.

The actor's legal troubles have had little effect on his popularity. "Two and a Half Men" remains America's most-watched TV comedy series and earlier this year Sheen negotiated a deal with network CBS that took his pay to a reported $1.8 million per episode.